You can just put the gain control at some random point like 3:00, but is that the optimal point? Not clear. One would need to know a lot about the circuit design to make that call. I’m not surprised AI isn’t getting involved in the answer, as it can be quite complicated. It’s also why few amplifiers actually have gain controls (except for vintage ones, and that was because of the wide variety of speaker efficiencies back then).I would have thought the least amount noise would come if the master is at or near full for loud listening, then the gain level if it is controlling the "tube gain" it’s then only increasing any noise to a minium level, as tube noise/distortion increases at the same rate as the gain will.
Cheers George