The only difference I can hear consistently, every time, is how my system sounds immediately after start-up and during the first twenty minutes or so. Definitely improves during that time. Have never been able to positively, consistently hear any improvement over hours of use with any gear except my cables and ICs. I also note the system sounds different at various times of the day or night and seems to sound its best on Saturday mornings before 10 AM.
Not taking sides in this thread, just stating what I've heard over time.
As always, YMMV.
Remember, it's just a hobby, not brain surgery.
Keep it light, keep it fun, have fun, happy listening :)