If using scientific instruments to measure things such as distortion, S/N ratio, and a lot of other specs used to present products as superior to others then that's scientific. Sure, a $20K plus system would probably sound better in the same room as one costing $1K. Maybe or maybe not.
I don't think the human ear is capable of discerning minute differences if the main goal is to learn what sounds best to the type of music listened to. Kudos to those who can afford very expensive equipment. But, the question of High End vs High Fidelity has an answer that can't ever be answered.