It sounds like whatever is behind the drywall is "hitting" the drywall as the drywall vibrates or vice-versa or the metal frame attached to the drywall is vibrating against the HVAC ducting. Pushing on the drywall either damps the drywall and/or pushes the two up against each other .. or both. Fortunately HVAC ducting does not care if it is bent :-)
Either use a drilling tool with a depth-stop and/or make one with layers of tape on a drill bit so you can drill the depth of the drywall and not further. Wrap on the drywall with your knuckles to try to get a feel where the vibration is. Drill a hole in the drywall there (assuming it is not an edge). Then push something blunt through the hole, an allen-key for example and see if something is right there. If there is, you can probably push something blunt like an allen key through the hole and push whatever is there backwards and then wrap your knuckles to see if it has stopped. If the HVAC is loose and sagging, then you may need to push it up, support it, then blow in some foam from a different hole. I am with jetter, don't go crazy if you don't know how much space is there.
Either use a drilling tool with a depth-stop and/or make one with layers of tape on a drill bit so you can drill the depth of the drywall and not further. Wrap on the drywall with your knuckles to try to get a feel where the vibration is. Drill a hole in the drywall there (assuming it is not an edge). Then push something blunt through the hole, an allen-key for example and see if something is right there. If there is, you can probably push something blunt like an allen key through the hole and push whatever is there backwards and then wrap your knuckles to see if it has stopped. If the HVAC is loose and sagging, then you may need to push it up, support it, then blow in some foam from a different hole. I am with jetter, don't go crazy if you don't know how much space is there.