Short answer, Yes.
Practical answer, Yes.
WAF answer, maybe.
Like millercarbon, I run a swarm, 2 10s and 1 12. I have a 15 in the garage, large, ugly and unused so far. I use one amp for all 3, utilizing a DBX 223XL crossover set at 40 hz. I plan to add another 12 or 10. The amp is a Denon POA 6600 mono block with 265 watts at 8 ohms.
Utility.
My goal was decent bass at low level listening, without needing to turn the subs up at low volume or turn the subs down at hi volume levels. All sub boxes are sealed or acoustic suspension as we used to say in the early 70’s. To save money, the boxes and speakers are sold/used for car stereo use. All of the above except the Denon cost less than my unused Velodyne 12 dedicated sub.