I can only add this... I have an Audio Research D160 tube amp from the early eighties, 1982 to be exact. It uses 6550 tubes biased to 65 mV, according to factory specs. Way to hot for any practical life. I have "detuned" them to 46-48 mV to calm things down while maintaining proper gain. The amp came equipped with two fans to bathe the tubes in cool air. And naturally, per the owner's manual, the amp takes a couple hours of use to achieve thermal equalibrium. Use this to your benefit. The detuning and the fans really help in this specific example.
Happy listening
Happy listening