And yet $100,000 CD players (and amps) are built on PCBs using generic copper, typically FR-4 substrates, though I have seen the odd PTFE, though their is little justification for it.
PTFE (Teflon like) insulated wire does not need to cost an arm and a leg, it is common for industrial and military uses and costs a fraction of "audio" wire..
Then again, using PTFE for hookup wire is pretty silly unless you are running twisted pairs (or similar). Individual wire runs don't benefit for a low dielectric constant. You need two conductors to have a capacitor, so if one wire is 10mm away from another wire, and you have 0.1mm Teflon insulation, the air is still by far the dominant dielectric.
If you are selling things and want to impress people who don't know any better, sure use expensive wire that will make no difference. However, if you are building your own stuff, every dollar you don't waste on wire can be used in places where it will actually make a difference.