What is the weight? If you go much above 70lbs per box, that is when the horrible handling of FedEx UPS creates a risk.
I shipped a pair of Zu Essences which are packed in like 4 inches of foam. I assume FedEx dropped one of the boxes off the back of the truck and the base of the speaker was damaged.
Palletizing and shipping via freight is better but far more expensive. If you ship those LTL, expect it to be $500+ for freight.
Best thing is to sell them locally.