Who is using I2S cables?

Thank you @jaytor . And yes, I understand a little bit re. the different configurations @lalitk mentioned. Which is why I was asking for smarter folks recommendations :-) 

If I read correctly, you noticed a significant improvement from AES to a $480.00 I2S cable https://www.highendcableshop.com/product-category/i2s-cables/ ?

So, two follow up questions: 

1. any chance you had an "A-B" experience with a high quality USB A to B connection and is the upgrade expense that big an improvement? 

2. re. a properly configured high end HDMI vs. the Tubulus Argentus I2S, you could tell a significant -- i.e., it was worth it -- improvement? 

Thanks much! 

I noticed a significant difference in my system switching from using an AES connection (DH Labs D110) to an I2s connection, initially using a basic $12 HDMI cable from Amazon. Switching from this cable to the Tubulus Argentus cable was an improvement, but more subtle. If I was on a tighter budget, I might have returned it, but I do like the sound. I have not tried other higher end HDMI cables. 

I currently have my Roon Server connected to the Gaia DDC using AQ Diamond USB. Inserting the Gaia instead of connecting the Roon Server directly to the DAC was a worthwhile improvement. I have not tried connecting the Gaia to the DAC with USB also. 

Making a list asap.

Thanks, @jaytor ! Appreciate the info.

I prefer l2s over USB including anything else my Holo Audio dacs l2s inputs pin outs are configurable to match just about any popular brand. Currently I’m using a generic brand of HDMI cable it’s surprisingly good .