This can go both ways; for years we made a kit version of our M-60 amplifier. Some people would do really well with it (you can see its layout in a video on the landing page of our website) and some people don't do so well- I've seen some that look like a rat's nest inside (quite often people who do this ask for more wire....). Its a simple fact that if the hand wired layout isn't clean and well thought out that it will not perform as well; the results can be highly variable.
Of course people like to open up a product and see a hand wired interior that is a work of art. I can safely say that we do that really well. But actually I think the internal appearance of our preamps is actually better than that of our amps.