IME, the answer is a little involved:
The Velodyne DD series subs have (DRC) software that is effective (when set up manually, the auto mode sucks) in smoothing bass response by correcting room induced effects. If you are listening to music only, "not that loud", then one 12" DD will probably be all that you need. Two will almost certainly be more than sufficient for that application in that room.
The JL has rudimentary software and SVS sells a separate (SVS-Audyssey) DRC box that is purportedly terrific. The same solution can be provided by any pre-pro equipped with Audyssey (or similar, like Anthem's ARC). HK also includes a variation in their HK990 integrated amp.
The caveat:
AFAIK, DRC is always managed in the digital domain. That means that your analog audio signal will see "ADC - room processing - DAC". I know that this does not appeal to many 'philes, particularly those using vinyl. In my book, the benefits of the software are worth the multi-conversion trade-off, but....
If you forego DRC, then 2 subs (if properly located) will provide smoother response than a single sub. You can place them so that room effects on one sub are (more or less) balanced out by room effects on the other. An extreme variation on this theme comes from A 'goner Duke at Audiokinesis, who sells a four sub solution called the Swarm. I haven't heard it, but, for a non- software corrected subwoofer system, it's the most conceptually appealing approach that I know of.
Marty
BTW You might also check out Ryhtmik. I use a pair of their 12" subs (w/ Audyssey) in my 2.2 channel, music only system and get great results.