In a balanced line system there is no need to lift the ground at one end of the cable.
Try not doing it in a large multi-room facility like a sound stage, dubbing room. It may not be required with the AES-48, but until all gear is to that standard, prudence takes precedence over valor.
Most XLR gear is not transformer coupled. Not all is actually balanced.
In transformer gear, an unbalanced signal is fed through the transformer. The output can be XLR, banana, TRS, multipin, etc., etc.
While the Jensen transformers are excellent, they, like all transformers, still have a sonic signature.
Depending on the issue, adding transformers with the screen carried may not solve the problem.