On my DS Sr. I used to have my Aurender (N100H) music server connected via USB. When I went to connect another device by coax it would not lock with the DAC because the DAC was still locked to the USB. The USB does not disconnect automatically and you can’t have two devices locked at the same time so I had to physically unplug the USB.
Maybe if you turn your computer off it will unlock and then the coax should lock when you select it as the input.
I now run my Aurender through a Matrix DDC which gives me i2s for connecting to the DAC.