Use a 250V rated fuse per the fuse holder as stated. 250V/5A
#2. AC 110: S5A... 110 is the AC Line voltage setting for the Amp when the wall outlet mains voltage is 110V - 120V. (S5A 250V fuse.)
Are you sure the fuse is a S5A? Using Google I could not find a S5A 250v fuse.
5A = 5 Amps.
S = ? Slow blow?