I have to agree with Eddie about the ST-style 45. Aside from driver use, the charm of the 45 is that it is really easy to make a superb, low-power amplifier with it. It has the cleanest distortion spectrum of any tube I’ve measured (closely followed by the 300B), but unlike the 300B or 2A3, it is super easy to drive. This makes two-stage amps simple ... in fact, I’ve yet to hear a bad 45 amp, while I’ve heard plenty of not-great 2A3 and 300B amps. Good 300B amps in particular are quite difficult.
45 amps also sound louder than you’d expect ... they easily keep up with 2A3 amps, despite what the numbers say. If 45’s were more abundant and at different price points, they would quickly find a market.
I have a dark suspicion that modern 2A3’s are simply below-spec 300B’s, and not related to original 2A3’s at all. Of course, that’s not really true, since 300B’s have 5V filaments while 2A3’s have 2.5V filaments. Modern 2A3’s are quite different than the bi-plate RCA originals ... I’m not sure where they fit, actually.
Returning to the 45 triode, I really think people would be surprised just how good 45’s sound, and how crisp and vivid they are. They are very different sonically than 2A3’s or 300B’s. They actually sound more like 845’s than anything else. Very clean and fast, no murk at all, and nothing like any pentode (no hash or grain). If you can get your hands on a good pair (or quartet) of 45’s, they are quite impressive and worth exploring,