Need a little help with Squeezebox Duet.

Is your router "B" or at least "G"? "B" may be too slow. Have you checked signal strength at the SB's location with a laptop or similar device?

When you change to a wired connection, have you changed the settings? You will still be connecting wirelessly if you don't reconfigure the settings.

Did you call Logitech's help line?

You can also get excellent advice from the forums at http://forums.slimdevices.com. They have a section for Duet users.

With a wireless connection signal strength is probably most important, but I have also found I get dropouts when there is a lot of unrelated traffic on the network, such as somebody else streaming a movie to their computer. Mlsstl makes a good point in regard to the hard wired connection - make sure that is what the Duet is using.

Per above; Network traffic could be the culprit. If it gets really frustrating you can move from a 2.4ghz base station/router to one of those broadcasting at 5ghz. There are other settings in your network preferences that dictate buffer size I believe. I had to fiddle with those as well, but do not remember the details. If you are using a printer or other device that uses the wires of your house as an antenna this also can interfere with the signal to Duet. Ultimately, if it is possible, you will avoid all these problems and get an audible improvement in sound by using an ethernet cable to connect your network to the touch.