ZYDO nailed it:
IN partcular:
" ... When someone sends a "lowball" offer, they know it. I don't really think anyone ever sells for that kind of price. .. Its a waste of time for both. ...I don't do it, and I personally find it irritating...."
IMO it goes well past simply "irritating" and takes it into "insulting" by all-too-many time-wasting bottom-feeders.
There used to be an honor code and an accepted /expected sense of fairplay in this hobby that is frequently now being ignored. These latter types also ignore the time honoured axion that says that if you are a pig you get fat, but if you are a hog you get slaughtered.
Result: I ignore the lowballers, also take note of them and brand them as such, and keep them out ad infinitum.