I find that transformers tend to obscure detail and they limit bandwidth. So if you have enough gain, an MC high gain phono section might be better if properly designed.
The loading of the transformer is critical, else it can ring (distort), making things brighter and obscuring detail. All the following is assuming that the transformer is properly loaded:
If you do not have enough output from your cartridge, most phono sections will loose some bass impact. Where a transformer will normally do that too, in this case they will win you some back.
If you have too much noise, the noise will obscure low level detail. Where transformer will also loose detail, it also gets you gain without noise, and so wins you back some of that low level detail.
So- its not something that you can always state what will work in all cases. Usually the manufacturer of the phono section will know if the cartridge you have will need a transformer or not.
If there was a panacea, I would state it but as a manufacturer myself that is well-known for not liking transformers, I'll be the first to admit that they can be very beneficial in a variety of situations!