But for someone who is trying to decide how best to allocate audio funds, just saying "system, system, system" isn't going to help that decision. Yes, synergy is huge, as I and others have posted many times.
I think Herman rephrased the OP's question nicely.
And so perhaps we should proceed from a perspective of "all other things being equal and understanding that it is ultimately synergy that matters most..."
In that spirit, I'd advise to focus on the phono, due to the difficulty of cleanly amplifying such a small signal from your turntable's cartridge. But pay particular attention to the cartridge-phono stage match, and the speaker-amp match. These are best thought of as pairs, since performance on each will depend greatly on what it is paired to.