Long distance from amp to speakers

As long as it doesn't introduce noise, you shouldn't be able to tell the difference. Years ago I had a 40' run of AQ Crystal in a bi-wire configuration & had the cable cut down to smaller sections when I was able to reposition the gear. I didn't notice a difference.

Ayre works very well with Cardas & in fact they use internal wiring by Cardas.

Monster cables should be fine - you are using an SS amp - so it is not much of an issue. What is the damping factor on your amp?

I also have this situation with a system of mine. I went with signal cable, and have been very happy.
I recently got a chance to audition several Nordost cables - I had to move the speakers closer, and they were 1/2 the length of the Signal cables. I started and ended the test with my 25 ft Signal cables.
I had to go to the level of Nordost's Frey until they were clearly superior to Frank's (Signalcable). That's a very big price difference to pay when you use long cables! I put to rest my fear of long runs with this test, though. And, I lust in my heart for a pair of 25 ft. Nordost Freys.

If your system is on the first floor and you have a basement under it, you can mount the amp on a platform in the basement just under the speakers any run a short run of speaker wire to the speaker through a small hole in the floor or baseboard. You would run a long interconnect cable from the pre-amp to amp.

I've never used this setup myself, but I've seen it mentioned here a few times.

Enjoy,

TIC

Sorry for saying so,but why would I need my wife to tell me,where to place my amps?Forget that, I wouldn't put my amps or arrange my system in sush away that it would degrade the sonics that I paid so much to achieve,just because she wants it.And then start looking for solutions to fix or correct,something that can be avoided all together.
George