Depends, as always, on the system. On my recent interim system consisting of my current Wadia, an Ayre AX-7e and B&W 804S speakers (no isolation gear or any of the other stuff I have now) I was using all kinds of low end cable with no issues (bettercables speaker cables, interconnects, Transparent basic Musiclin)k. When I moved up to my current system configuration I nearly went deaf from the horrid sound. I upgraded the cable and all was well. In the end, the improvement was beyond measurement.
Monster cable and power products will make your face melt (and not in the Jack Black good way).
Monster cable and power products will make your face melt (and not in the Jack Black good way).