if you go with a single run you will need a better jumper to get the best sound. Some would recommend a single run of better wire and others will recommend bi wire of a lesser quality (for the same price) The bi wire config will give better bass (usually IMO) just because of the greater cross section of wire
bottom line is you will get a million different answers it is best to buy used and try for yourself.
bottom line is you will get a million different answers it is best to buy used and try for yourself.