I agree, cable lifters are definitely an 'Emperor's new clothes' item ;--) Except in two instances:
1.) Always use them when you have an electric radiant heating grid under the floor (and it's turned on ;--) and
2.) Sometimes, lifters can make a difference when you have a steel-mesh (or re-bar) reinforced concrete slab-on-grade. This is not a slam-dunk tweak, and depends a lot on the speaker wire and/or the single ended (not balanced) IC's being used. Do a dry run with any nonmetallic blocks (bricks or wood 4x4 pieces or small cardboard boxes.) If you roll 'snake eyes' you don't have anything to return ;--)