Many cable effects are dependent on interactions between the characteristics of the cable and various technical characteristics of the particular components they are connecting, some of which are unspecified and unpredictable.
Also, I would not assume that the "best" cable is necessarily the one that is most expensive, if that is what you are thinking.
Therefore there is no "one size fits all" answer, and the only way to tell with any certainty is to try it both ways.
IMO.
Regards,
-- Al
