If you have a mega dollar system, by all means better cables can make a difference although I never heard a huge difference myself, there is a difference. That said,
butting the high dollar cable money into the equipment will get you a bigger bang for the buck.
Putting a system together that sounds good takes time and effort in your price range. Any system done right will get good sound. Your room also plays a part in it.
No hype, no sarcasm, just facts..