We are talking engineering here, not basic science. Engineering uses the best estimates for how to get something done. In engineering there is always the safety factor, something added just in case the formulas lack something.
If as Eldartford suggests, Pabelson is correct that science knows but audiophiles don't, then why is there not just one best cable, one best speaker, one best amp. As engineering exercises with given price points, all amps, cables, speakers are compromises given the limits of technology. Engineering within the limits of what science has researched can tell us what considerations need to be made in designing a speaker, but not how to build the best speaker.
While I recognize Eldartford's science background, most who post here and claim science background's don't have them. Those with no scientific training should not recognize assertions, such as science knows just audiophiles don't. For most this is shear hubris and bullshit. They don't know but believe in common sense not science.