As I mentioned before, the Infinity IRS-V's are the best sounding speakers i've ever heard, though in many ways my current Magico S5's are better. The S5's don't have the dynamic headroom of the Infinity's, nor the 3d imaging or off-axis performance, however they are more resolving of inner detail from the low bass region to lower mids, they have more texture and body than the fives & are more seamless and coherent. There is also a greater quality to the sound which is to be expected given the S5's superior drivers, crossover, cabinet & internal wiring. The S5 is also more room friendly in terms of placement. So it depends on how you define "best".