Perhaps a slightly skewed example, but I own both a gainclone and class-A amp built by Tim Rawson. The gainclone being a dual-mono 200watt, the class-A a 15watt Aleph clone.
Which I prefer depends on my mood and music being played.
Strengths of the gainclone; Smooth mids and highs with "Reach out and touch it" transparency, stunning soundstaging front to back/side to side with pinpoint imaging.
Strengths of the Aleph; Perfect tonal balance top to bottom, more weighty presentation overall lends to more natural sounding vocals, strong articulate bass.
Both remarkable amplifiers, neither of which I'd easily part with.