Hce4,
I see that you are contemplating using the VTL MB-450s.
My friend used to use the VTL MB-450s with his Eidolon speakers, before he upgraded to the Lamm M2.2s. The VTLs are very musical amps, with great mid-range and a well extended treble. The bass response is very good too.
However, two things kept me from getting these amps when it was my time to upgrade.
One, was the heat. These amps run hot. (Even hotter than the Lamms run, which is my only gripe about the Lamms actually, as they run very warm.) In the summer, we used to have to open a window and run a fan with the VTLs running, whereas now, with the Lamms, we just have to open the window. (FYI, we live in California, where it is usually fairly warm all summer.) That is only a problem for 4 months or so out of the year though. (However, for a couple of months out of the year, it helps reduce the heating bill!)
Two, the bass response of the VTLs, while very good, (especially for a tube amp), was not in the same class as the Lamms. The Lamm bass response is quick, tight and deep. The VTLs did not go as deep, nor were they as quick and tight. Although for a tube amp, I must say they did quite a good job.
It might not be fair to compare the two amps, as the VTLs usually runs around $4,500 used, whereas the Lamm M2.1s (the M2.2s predessecor, which has the same bass response as the M2.1s) run about $7,000 used, which is about 50% more. (The M2.2 run closer to $12K used.) However, if you want the best bass response....
The reason I bring this up, is that one of your original points for upgrading was that you wanted "stronger bass output", and I did want to point out that while the VTLs have good bass output, it is not great bass output. As we had done a direct comparison between the two, I thought you might be interested.
My two cents worth.
Good Luck in your search.