As someone said it depends on your speakers, source components (tube or SS or hybrid). The type of amp is going to sway the sonic signature more than the preamp, imo.
I am using a Spectron MK w/V-Cap upgrade that is very musical and not SS or tube sounding. I paired it with a Audio Research LS26 and am happier with the sound vs. the SS preamp I have before. My souce components are a Cary 303/300 and a Magnum Dynalab 609T tuner; the speakers are B&W 803D and the diamond tweeter is much 'friendlier' than their non-diamond tweeters.
I've listened to McIntosh tube amps like the 501 monos with the speakers but miss the speed, overall headroom and soundstage and bottom end punch of the Spectron MK2 (the V-Caps make the amp more liquid sounding).
So,imo, start with speakers you like and then try them with electronics (tube or better SS) until you decide what you like long term.