Unless your amp is of the "audobias" type (primaluna is one brand) then you will have to readjust the bias. Matched tubes just means that they are very similair in terms of operating characteristics. Important! If your amp has only one bias adjustment for each channel then it's recommended that you ONLY buy matched tube sets and replace them all when one goes bad. RAM tubes website has a good primer on matched tubes.
Cheers!
Cheers!