There are valid engineering reasons for designing monobloc amps and I imagine that sonic benefits thereby flow. But if mono designs are really that much better then why aren't all ultra high end electronics monobloc designs? Where are the monobloc phono preamps, D/A converters or preamps?
For all those people using long interconnects/short cables, how do you deal with placing delicate, vibration sensitive electronics so close to your full range vibration creating speakers? There's also the issue of power amp transformers and woofer magnets/crossover components interacting due to their close proximity. I don't know this for a fact, but maybe long interconnects/long cables is really the way to go? Just something to think about.