Mick, I have tried both of your options and found locating a subpanel just outside the room vs next to the main panel by far the easiest and least expensive. Once your subpanel is close at hand, it is quite simple to run separate dedicated and star grounded circuits to each component which minimizes any interaction between them (see diagrams in my system).
Plus, by putting the subpanel on an 4kva iso transformer, I found it eliminated the need for separate or multiple power conditioners, eliminated any possibility for ground loops, and minimized the need for exotic and expensive PCs.
I assume you have a fairly simple way to route the power line to the subpanel and a way to hide the subpanel in the room? If you do explore the iso transformer, be aware that they to make an audible humming noise that would need to be taken into account.
Plus, by putting the subpanel on an 4kva iso transformer, I found it eliminated the need for separate or multiple power conditioners, eliminated any possibility for ground loops, and minimized the need for exotic and expensive PCs.
I assume you have a fairly simple way to route the power line to the subpanel and a way to hide the subpanel in the room? If you do explore the iso transformer, be aware that they to make an audible humming noise that would need to be taken into account.