long speaker cable run or long balanced IC ??

All very helpful.

I will most likely me driving aerial lr5 ( power hungry) with a wyred4sound preamplifier (80-113 ohm output impedance). Amps will most likely be wyred4sound high powered mono blocks (sx-1000)

While I realize the speakers are a rough load, not sure if this is considered high or low output impendence for the pre.

Seems like the short speaker cables make the most sense.

Yes, the preamp output impedance is quite low, for purposes of deciding about cable lengths.

The main concern is that it should be low enough to avoid significant interaction with cable capacitance, which would roll off the highs, and result in sluggish transients. A preamp output impedance of 100 ohms or thereabouts is easily low enough to avoid that, in relation to the capacitance of any length of cable that is likely to be used in a home environment (even 50 feet or more).

Combine that with the fact that the interface is balanced, which will minimize or eliminate noise pickup and ground loop issues that might otherwise be sensitive to cable length, and it sounds to me like the choice is clear.

Best regards,
-- Al

Quicksilver Audio's Fullpreamp has an output impedance of only 1.5 ohms. The previous version of this preamp has an output impedance of 12.5 ohms. Most likely the reason these preamps match well with whatever amplifier you decide to use and long interconnects are obviously not a problem.