40+ watts SET, cost is not a problem

There is a Golden Tube Audio SE40 amp available now on eBay for $1000. It uses three 6L6GC beam tetrodes in parallel per channel It is single-ended, no phase splitter. I own one. Tube replacement is far less costly than 300B's, 211's, 845's ... You might want to check it out.

@larryi ,

You mentioned:

“The best sort of higher-powered SET amps I heard were Audio Note Gaku-On monobloc amps (parallel 211 SET) that sounded great with a wide range of speakers, including somewhat difficult speakers like Harbeth 40.3s.  But, those amps cost as much as a house.”

Would the Audio Note Jinro 211 Set amp maybe be a possibility also , for less money?

@larryi when you refer to gaku-on, are you suggesting Kondo or AN UK?

Secondly, which other tube amp (non-SET) would you suggest with at least 80-100 watts which have top tier sound?

I have heard the Jinro in several systems, including one with AN-E speakers where I am familiar with its sound.  The Jinro is a good sounding amp, but, it seems just a bit too laid back and not as exciting and vivid as I like.  

For a non-SET amp with 100 watt or so power, I am a big fan of the Synthesis Audio A100 amp (KT 66 tube).  This is a punchy, lively, and warm sounding integrated amp that also has a built in DAC that is pretty decent.  That it is a screaming bargain makes it hard for some people to consider it in a very high end system.  Perhaps one of the Synthesis separates, then, for those who want to spend more than the price for the A100.  

The Gaku-On that I am familiar with is an older Audio Note (uk) amp.  It is a quite versatile amp that sounded good with any speaker I heard it paired.  I have not heard much Kondo gear.  The one extensive experience I had was when I auditioned a pair of Stax 007 Omega2 headphones.  I bought the headphones based on the audition, but, when I told the dealer I was not getting as good sound from the phones as I heard in his audition, he replied: "of course not, you heard them through a Kondo M-10 and you don't own anything like that."

@pani A 40 Watt SET will have real problems making bandwidth. That is why the smaller SETs sound better as @larryi  pointed out.

Do yourself a favor- if you want to get the most out of your amplifier dollar, its not going to happen with an SET of that sort of power, and throwing more money at it won't overcome the problems you have with the larger output transformers needed to make that sort of power (and output transformer designer can tell you this). Either get a speaker that can be driven easily by an SET of much less power, or get a PP amp that can do the job properly.

There is no reason a PP amp can't be every bit as musical and involving as the best SETs out there; power notwithstanding. Its all a matter of good engineering and execution.

Here is something else to think about: when SETs are compared to PP its usually apples and oranges. The PP amp likely isn't class A, uses pentodes and probably also has feedback. How about level the playing field? How about a PP amp that uses the same power tubes as the SET, is also class A and zero feedback? When you level the playing field in this manner, you find out real quick that SETs just really aren't that good, while the power tubes themselves really are. Do you see what I'm saying?