I have a Node 2i, and recently upgraded the coax SPDIF cable and there certainly was an improvement to my ears. I went from a budget Blue Jeans Cable to a Kimber D60. You’re starting from a higher plateau, but the question was will I hear a difference in SQ- you will, but you may have to try a few to find what suits you. In my case the brighter, more detailed D60 was complementary to my warmish system.