Nominal impedance is so because of the specific operating frequency that the measurements are taken. Obviously, a cable designed to convey a 500MHz Manchester encoded digital signal will be capable of conveying audio spectrum just as well, but noise rejection is not a strong suit of unbalanced cables to begin with. Better quality cables are made with two inner conductors (a pair) of the same wire, and an outer foil shield surrounded by 100% braided shield with a drain wire. The two inner conductors go to the signal hot and signal ground respectively on each side, and the drain wire is either connected to signal ground on the source side, or (better) to chassis ground to protect from noise infiltration on both of the signal carrying conductors. The only way to improve on this is taking the leap to XLR connectors and fully balanced differential circuits, but that’s not always practical to do.