You are going to take a hit - how big a one and how much you notice depends on how loud you typically listen to the front channels and the size of your room. There is no way the Marantz is going to match the KW500 for lack of compression at volume, woofer control, and nuanced performance. In your favor, the Focal's are very efficient, but you will still notice a difference in dynamic head room and detail retrieval in any case. I would think to come close to matching the performance of the KW500 for two channel listening, you would need to go with the Denon A1HDCI pair of separates, but that is getting incredibly expensive - 15 grand retail.
I might suggest replacing the mid-grade Onkyo with the top Marantz, Onkyo, Sony or Yamaha receivers and ditching the KW500 for either: a large integrated that provides HT bypass (e.g. Plinius Hiato), a good but relatively reasonably priced two channel power amplifier (e.g Parasound JC1 or PLINIUS SB-301), or a pair of Musical Fidelity Supercharger 550K's in line with the receivers front outputs. I think the big integrated will be the best for you because it completely bypasses the multichannel preamp in the receiver for 90% of your listening (assuming you have a dedicated two-channel source hooked up to the integrated), and would allow you to use the superior amplifier in the integrated for the front speakers in HT mode. As good as these new AV receivers and even separates are, they cannot run with the better dedicated two channels integrateds IMHO.
I might suggest replacing the mid-grade Onkyo with the top Marantz, Onkyo, Sony or Yamaha receivers and ditching the KW500 for either: a large integrated that provides HT bypass (e.g. Plinius Hiato), a good but relatively reasonably priced two channel power amplifier (e.g Parasound JC1 or PLINIUS SB-301), or a pair of Musical Fidelity Supercharger 550K's in line with the receivers front outputs. I think the big integrated will be the best for you because it completely bypasses the multichannel preamp in the receiver for 90% of your listening (assuming you have a dedicated two-channel source hooked up to the integrated), and would allow you to use the superior amplifier in the integrated for the front speakers in HT mode. As good as these new AV receivers and even separates are, they cannot run with the better dedicated two channels integrateds IMHO.