Hi @mikepaul , REL has nice little videos on this. Definitely use the high level inputs with the Speakon connection at the sub end. Tap off of the speaker outputs on your amp as shown. I have two subs, and use red to positive and black to negative on the amp’s speaker outputs. The yellow is taped off. One sub to left and one to right. There are separate instructions for using only one sub. On your Duo you can double up with both speaker and sub connected to same output; you can use bare wire on the sub wire, or add banana plugs if your speaker wires are spades etc.
The high level connection is the way to go. Then there is a video on adjusting the sub’s phase, roll off and level. I love my REL subs.