Need cable advice tome reduces mids

Would be helpful to know what equipment is in your system. That said, sounds like you might benefit from trying some silver interconnects, but they tend to be above what you’re looking to spend. BUT, I recently discovered LavriCable out of Latvia and they’re selling 5N silver interconnects at more than reasonable prices that might help tighten up your midrange situation. I’ve got their Reference XLR interconnects and they’re excellent — detailed yet natural sounding and no bloat anywhere but still with very good tonality. Their 1m Reference costs $154 per pair and the Ultimate that employs 40% more silver wire goes for $234 per pair. I’d go for the Ultimate if you can swing it. Several others here have since tried LavriCables and everyone so far has been pretty thrilled with the improvements they’ve brought to their systems. Just one under-the-radar option to explore, and best of luck in taming your midrange issue.

https://www.lavricables.com/cables/reference-silver-xlr-interconnects/

https://www.lavricables.com/cables/ultimate-silver-xlr-balanced-interconnects-2/

Yes, what is your system and venue. There is a place to put photos and your components under your UserID. This would be helpful as there are lots of variables that could cause your problem.

@dtapo so few thoughts on this…

1. Your earlier post on new amp causing fatigue. Amplification in question is Denafrips, correct?
2. Your Canare cables are neutral. They don’t emphasize any particular bandwidth or frequency range. They’re not the best cables in the world but by no means are they contributing to this

3. You have kit speakers that you built, correct?

The fatigue you’re talking about in your posts is usually a result of overemphasized presence region. It’s not just mids. It’s a hump in that frequency region and the only way to get rid of it is to remove the component that’s causing it. Your amp/preamp/speaker combo is not a good match. 
My recommendation would be to dump the amp and potentially even change the speakers. No cable will fix this issue. I would also not entertain band-aid type solution such as an equalizer to remediate this problem. If you continue to use this system you might even end up damaging your hearing. 
 

You have a Hegel amp that without the same system doesn’t cause this problem and if that’s the case it just proves what I’m saying here is correct. 
 

That’s all I got for now. You decide. 

 “within” the same system is what I meant to say…autocorrect had other thoughts obviously…

audphile1  I believe you are correct, that it's the synergy between these components causing the problem. I was hoping that there would be a solution and I could salvage the system. In my listening sessions, the peaks never go above 75dB, so it's not a "loudness" problem.