Question for amp experts

Absolutely.
Yes, as Millercarbon say, there are some space and cooling limitations to an active speaker, but with money, many can be overcome. So in theory, not impossible at all. And as also noted, there are significant opportunities when one can fully characterize both the load and the transfer function of the speaker - and in effect compensate for those irregularities.  In a cheap, mass-fi world this is precisely what Bose does and what every expensive in-car manufacturer does. Why? because cars are insanely irregular acoustic environments and benefit dis proportionally.  While i have not heard the latest, i think the flagship Meridian system is a case for the active approach.
Now most active speakers are far more compromised, but we must still compare an active speaker at $2k, with, say a passive speaker at $1k and a relatively modest -- and imperfect -- power amp at another $1k. Better? dunno - let your ears judge.  A simpler package? You bet. And for some that will win right there.
Control theory is a powerful concept. It is the basis of most rocket science and robotics and self-compensating weapons. Active speakers are how one implements control theory in the music world.
Whether the practitioners get it right is another question.
G

That depends on the money , and compared to what 
If is hooked up internally just using a module and internal digital board no.

Many commercial loudspeakers speakers are active designs.  Think concerts, studio monitors, etc.  

I think digital actives like those from Meridian are really impressive and worth a listen.  You have to remember that you are getting a dedicated amplifier for each speaker driver.  Everything is matched by design.  The older Meridian speakers like DSP5000s, 5500s and 6000s all use class A amplifiers, and are available on the used market at a fraction of their original prices.  It can be a lot of trial and error (and $) to match speakers, amps, components and cables in a conventional system.

To address an earlier point, the components need not be in the speaker cabinet for an active speaker design- NHT had an active model where the electronics were in a module separate from the speaker cabinet.

Anybody who thinks a class d amp sounds good has never heard a good amp. Anyone who thinks an amps chassis makes no difference has never heard a great amp.

" While i have not heard the latest, i think the flagship Meridian system is a case for the active approach."

Not even close.