Some of the active speakers have DSP for desktop placement. The isoaccustic stands really help on a desk for passive speaker. Likely active speakers with DSP too would be helped.
IsoAcoustics ISO-200Sub Isolation Stand; ISO-200 Sub - The Music Room (tmraudio.com)
After some experimentation with the following speakers on my desk,
KEF LS50
KEF LSX
Audience 1+1
AudioEngineUSA 2
I realized that the best way to have speakers in an office with a desk is to have the speaker BEHIND me. I have 6 monitors hooked up to a silent PC and the KEF LS50 META speakers behind me. It is a great sounding room. I have OLD photos on my Virtual System.