The synergistic Research Fuses are Quantum tunneled in one direction-
from the "S" of the word Synergistic towards the "h" in the word Research. So at least this corresponds to the arrow of some other fuses. You want Current to flow from the capital "S" towards the other end of the fuse where the last letter "h" is.
So on some fuse holders ( like the tray type holder next to power cord connectors) , it is easy to figure out the "hot" side and the "neutral" side and put the fuse in in the optimum position on the first try. The other spots one has to experiment for optimum results.
I hope this helps.
David Pritchard