By what margin do you prefer tubes? If its by a considerable margin (like me) then create a list of tube friendly speakers to audition. Keep in mind that a lot of speaker manufactures claim that their speakers are tube friendly because they dont want to lose that market - and yes, they will play music with tubes, and probably sound pretty good; but when you hear claims that tubes are, overly euphonic, lack dynamics or cant do bass, thats because they have been paired with speakers that require the amplifier to operate outside its ideal ratings - and that happens a lot. Tube amplifiers are not nearly as flexible as solid state amps, but inside their comfort zone can be just as lively. Tube watts are expensive. Take that into consideration when determining the specifications of your speakers. You can save a bundle in tubes by keeping the efficiency up. Ask Charles1dad about 300b tubes - you dont want to need eight of those babies.
If you just kind of prefer tubes but solid state can float your boat, my advise is to go solid state - unless your a pyro.