I think that it is quite possible that small signal tubes that can compete with NOS tubes could be manufactured again. Tube gear is very popular again so there is plenty of profit to be made and with the design and testing technology available today it could happen. They would be different from vintage tubes just as a car made in the 50s is different from one made today, but both have their strong points.
On another point, a vintage tube does not have to be NOS to sound as good as a NOS tube. Many tubes sold as NOS probably are used. But if they are still in like new condition they can sound as good as tubes that haven't been used and can last as long. Nobody kept track of most tubes made in the 50s and 60s to document if they were ever used.
To get good ones you either need to buy them from a reputable dealer who tests them or take your chances buying on ebay (where there are both reputable sellers and crooks) and test them yourself. There are pros and cons to either strategy.
On another point, a vintage tube does not have to be NOS to sound as good as a NOS tube. Many tubes sold as NOS probably are used. But if they are still in like new condition they can sound as good as tubes that haven't been used and can last as long. Nobody kept track of most tubes made in the 50s and 60s to document if they were ever used.
To get good ones you either need to buy them from a reputable dealer who tests them or take your chances buying on ebay (where there are both reputable sellers and crooks) and test them yourself. There are pros and cons to either strategy.