Leaving the tubes burning all the time will not damage anything except for shortening the life of the tubes. Tube life is (normally) anywhere from 2,000 to 10,000 hours so figure on replacing the tubes at least once a year or as much as 4 times a year for some. Tube amps sound their best, IMO, after they're on for 48 hours.
As for biasing yourself, the only thing I can add is to be mindful of your warranty: it might not cover audiophile-induced shorts.
As for biasing yourself, the only thing I can add is to be mindful of your warranty: it might not cover audiophile-induced shorts.