Experience using Spectral without MIT or preamp

"the president of Spectral is good friends with the president of MIT, so maybe that explains it" Only partly.
Experiment, if you must, with care & VERY low volume.
The Spectral is a wide-bandwidth design and will thereby accept input signals in the MHz region. Spurious signals entering the system in the very high hi's could send the amp into oscillation.
That PARTICULAR mit cable allegedly rejects such signals, so is recommended. It cuold have been another cable producer, maybe that's where the friendship comes in...

For the record, I've tried Spectral amps w/out a pre and with another pre (through cdp). While I detected no problems -- visible (i.e. drive units excursions) or audible -- I was in a relatively "clean" zone... the system picked up noise from a cell phone though, so nothing is "invulnerable". And I was playing at "whisper" volumes just to be safe!

For best results, use something other than zip cord as a speaker cable, install a Zobel network ( resistor & capacitor ) at the speaker terminals and don't worry about it. Sean
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I'm using Wadia 6 CDP directly connected to DMA 150 power amp with MIT MI350 interconnect cables, which is not the correct one that Spectral recommended. But I'm using Spectral recommended MH770 speaker cables between DMA 150 and Spandor 3/5A Speakers.

With small and big volumes, sound's very clear and wonderful. And can't find any troubles in my system.

I'm going to add Spectral pre amp to my system because system with pre amp can give me better Spectral sound.