OK. I know this is an old thread, but I must mention that I'm doing this. I'm using two relatively identical preamps (a Audible illusions 3A and a 3B).
The 3B is the main switching hub (all inputs connect here), and it drives two 100 watt tube monoblocks (high frequencies, passive crossover soldered into the input wiring). I use the buffered tape-outs of the 3B to feed the AUX input of the 3A, and that feeds two 200 watt SS bass amplifiers. The Audible Illusions preamps use precise stepped attenuators, so level matching is not a problem.
Sound? Incredible. Advice to the contrary, if you have the appropriate equipment, go for it!
I should note the the speakers I use -- Magnepan IIIAs -- are designed to optionally operate with a simple, passive high pass filter for biamping.