Dummies guide to connecting a REL Strata III Sub

I would like to connect a sub (maybe two) to my system, but I cannot go through the preamp because it is mounted in a little closet in my listening room and I have put my speaker wire in the wall to hide them (I know....I can hear the growning from the audiophiles....but had to do it....WAF).

Anyway, given this restriction, how can I connect a Sub (or two) to my system? Do I go from the sub, to my speakers and then my speakers to the my speaker connector wall plate (where my speaker wire is ported) -- which is ultimately connected to my amp in the closet?

Also, can anyone tell me if the REL Strata III is capable of being connected via the speakers using speaker cable and bipassing the preamp all together?

Last but not least, by bipassing the preamp, will this cause any sonic deficiencies?

I need step by step instructions! :)

Thanks,

Mike