I most definitely noticed an improvement by running two dedicated lines (one for amps, and one for source/pre). But then, I am running several high current amps (two Adcom GFA-555II's in bridged mono, one Adcom GFA-2535, with two of the channels bridged mono), and the one (non-dedicated) line I had been using couldn't provide all the juice that I needed. While I feel that installing the two dedicated lines was the main improvement, I have also incorporated all PorterPorts, all DIY power cables (from Ernie Munier), and PS Audio Ulitimate Outlets on each line (with a HC model for the amps, and with PorterPorts installed for the two non-HC models). I believe that all of these components have been beneficial to my setup. Also, FWIW, my dedicated pre/source AC line is 12AWG Belden, and the line for the amps is 10AWG Romex (the 9AWG Belden was too pricey for me).
Hope this helps, Tom.
Hope this helps, Tom.